Named after Enrico Fermi - Italian-American physicist; Nobel laureate (1901-1954).
Fermi is a large lunar crater of the category named a walled plain. It lies on the far side and can not be viewed from the Earth. Thus this feature must be viewed from an orbiting spacecraft. The most notable aspect is that the large and prominent crater Tsiolkovskiy intrudes into its southeastern rim. (wikipedia entry)
A crater is a circular depression likely created by an impact event. On the Moon they are named after deceased scientists, polar explorers, astronauts or cosmonauts.